Analysis into conolidine has resulted in discovery of the opioid receptor in the body called ACKR3/CXCR7. ACKR3 seems to be one of the most wanted focus on for conolidine, which also disregards another 4 classical opioid receptors(3).Hepatotoxicity: Having overdose amounts of acetaminophen will bring about serious harm to the liver and from time t